MicroRNAs and Parallel Stem Cell Lives
نویسنده
چکیده
A new study by Shimono et al. (2009) demonstrates that certain microRNAs that regulate the self-renewal factor BMI1 are downregulated in purified populations of normal mammary epithelial stem cells and breast tumor-initiating cells. These findings have important implications for the regulation of self-renewal and differentiation by microRNAs and suggest new ways of targeting cancer stem cells.
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عنوان ژورنال:
- Cell
دوره 138 شماره
صفحات -
تاریخ انتشار 2009